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    Alfa α1-Antitrypsin


    Test Details


    • Acute Phase Proteins
    • Alpha1-Protease Inhibitor


    Detection of hereditary decreases in the production of α1-antitrypsin (α1AT). Decreased or nearly absent levels of α1AT can be a factor in chronic obstructive lung disease and liver disease. An increased prevalence of non-MM phenotypes is found with cryptogenic cirrhosis and with CAH. Cirrhosis in a child should raise consideration of α1AT deficiency or Wilson’s disease. Diagnosis of inflammatory states, if elevated (eg, rheumatoid arthritis, bacterial infection, vasculitis, neoplasia).

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