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    Prothrombin Time PT
    May 24, 2018
    Prostate PSA
    May 24, 2018
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    Protein Serum


    Test Details


    Evaluate nutritional status; investigate edema.

    In the entities which follow, the diseases listed are sometimes increased or decreased as indicated, but are not always so.

    Causes of high total protein: dehydration; some cases of chronic liver disease, including chronic active hepatitis and cirrhosis; neoplasms, especially myeloma; macroglobulinemia of Waldenström; tropical diseases (eg, kala-azar, leprosy, and others); granulomatous diseases, such as sarcoidosis; diseases in which total protein is sometimes high include collagen disease (eg, systemic lupus erythematosus (SLE), and other instances of chronic infection/inflammation).

    Causes of low total protein: pregnancy; intravenous fluids; cirrhosis or other liver disease, including chronic alcoholism; prolonged immobilization; heart failure; nephrotic syndromes; glomerulonephritis; neoplasia; protein losing enteropathies; Crohn’s disease and chronic ulcerative colitis; starvation, malabsorption or malnutrition; hyperthyroidism; burns; severe skin disease; and other chronic diseases.

    Very low total protein (<4 g/dL) and low albumin cause edema (eg, the nephrotic syndromes).

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