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    Alkaline Phosphatase, Serum
    May 20, 2018
    Amylase, Serum
    May 20, 2018
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    Alpha-Fetoprotein (AFP), Serum, Tumor Marker


    Test Details


    • AFP, Serum
    • Alpha-Fetoprotein (AFP), Serum, Tumor Marker


    The most important application of AFP testing in cancer management is for testicular cancer. Although not present in pure seminoma,1 elevated serum AFP is closely associated with nonseminomatous testicular cancer.2-4 The measurement of AFP in serum, in conjunction with serum hCG, is an established regimen for monitoring patients with nonseminomatous testicular cancer.5-8 In addition, monitoring the rate of AFP clearance from serum after treatment is an indicator of the effectiveness of therapy.9,10 Conversely, the growth rate of progressive cancer can be monitored by serially measuring serum AFP concentration over time.11 Serial serum AFP testing is a useful adjunctive test for managing nonseminomatous testicular cancer.

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